Plaza Menacho, I. : rechercher sur Z-Library

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1

[IEEE 2018 Learning With MOOCS (LWMOOCS) - Madrid (2018.9.26-2018.9.28)] 2018 Learning With MOOCS (LWMOOCS) - Local MOOC Solution for Thight Budgets or Limited Internet Access

Plaza, Pedro, Sancristobal, Elio, Carro, German, Blazquez, Manuel, Menacho, Antonio, Castro, Manuel, Perez, Clara, Garcia-Loro, Felix

Année:

2018

Langue:

english

Fichier:

PDF, 13.27 MB

english, 2018

2

[IEEE 2019 IEEE Learning With MOOCS (LWMOOCS) - Milwaukee, WI, USA (2019.10.23-2019.10.25)] 2019 IEEE Learning With MOOCS (LWMOOCS) - Portable Blended MOOC Laboratory

Plaza, Pedro, Sluss, JIm, Meier, Russ, Castro, Manuel, Sancristobal, Elio, Carro, German, Blazquez, Manuel, Menacho, Antonio, Garcia-Loro, Felix, Perez, Clara, Munoz, Javier, Tovar, Edmundo

Année:

2019

Fichier:

PDF, 945 KB

2019

3

[IEEE 2020 IEEE Global Engineering Education Conference (EDUCON) - Porto, Portugal (2020.4.27-2020.4.30)] 2020 IEEE Global Engineering Education Conference (EDUCON) - Visual block programming languages and their use in educational robotics

Plaza, Pedro, Peixoto, Aruquia, Sancristobal, Elio, Castro, Manuel, Blazquez, Manuel, Menacho, Antonio, Garcia-Loro, Felix, Carro, German, Munoz, Javier, Munoz, Monica, Munoz, Alejandro, Munoz, Sara,

Année:

2020

Fichier:

PDF, 220 KB

2020

4

Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance

Plaza-Menacho, I, Morandi, A, Robertson, D, Pancholi, S, Drury, S, Dowsett, M, Martin, L-A, Isacke, C M

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 943 KB

english, 2010

5

Localizing a putative mutation as the major contributor to the development of sporadic Hirschsprung disease to the RET genomic sequence between the promoter region and exon 2

Burzynski, Grzegorz M, Nolte, Ilja M, Osinga, Jan, Ceccherini, Isabella, Twigt, Bas, Maas, Saskia, Brooks, Alice, Verheij, Joke, Menacho, Ivan Plaza, Buys, Charles HCM

Journal:

European Journal of Human Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 159 KB

english, 2004

6

Re: “Inhibition of medullary thyroid carcinoma (MTC) cell proliferation and RET phosphorylation by tyrosine kinase inhibitors”

Ivan Plaza Menacho, Jan Willem de Groot, Thera Links, John Plukker, Bart J.L. Eggen, Robert Hofstra

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 40 KB

english, 2004

7

Cellular effects of imatinib on medullary thyroid cancer cells harboring multiple endocrine neoplasia Type 2A and 2B associated RET mutations

J.W.B. de Groot, I. Plaza Menacho, H. Schepers, L.J. Drenth-Diephuis, J. Osinga, J. Th. M. Plukker, Th. P. Links, B.J.L. Eggen, R.M.W. Hofstra

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 354 KB

english, 2006

8

Current concepts in RET-related genetics, signaling and therapeutics

Ivan Plaza-Menacho, Grzegorz M. Burzynski, Jan Willem de Groot, Bart J.L. Eggen, Robert M.W. Hofstra

Journal:

Trends in Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 745 KB

english, 2006

9

RET in breast cancer: functional and therapeutic implications

Andrea Morandi, Ivan Plaza-Menacho, Clare M. Isacke

Journal:

Trends in Molecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 508 KB

english, 2011

10

N.P.2 04 Patients with spinal muscular atrophy (SMA) and healthy siblings sharing homozygous deletions of the SMN1 gene reveal an identical number of SMN2 gene copies but different SMN protein levels

H.H. Lemmink, Y.J. Vos, I. Plaza de Menacho, J. Dijkhuis, N.V.A.M. Knoers, M. de Visser, C.H.C.M. Buys

Journal:

Neuromuscular Disorders

Année:

2006

Langue:

english

Fichier:

PDF, 42 KB

english, 2006

11

73 Proffered Paper: Glial Cell Line-derived Neurotrophic Factor (GDNF) Signaling as a Target for Endocrine Therapy Resistance in Breast Cancer

A. Morandi, Q. Gao, P. Francica, A. Mackay, J.S. Reis-Filho, M. Zvelebil, M. Dowsett, L.A. Martin, I. Plaza-Menacho, C.M. Isacke

Journal:

European Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 66 KB

english, 2012

12

Identifying Candidate Hirschsprung Disease–Associated RET Variants

Grzegorz M. Burzynski, Ilja M. Nolte, Agnes Bronda, Krista K. Bos, Jan Osinga, Ivan Plaza Menacho, Bas Twigt, Saskia Maas, Alice S. Brooks, B.G.M. Joke Verheij, H.C.M. Charles Buys, M.W. Robert Hofstr

Journal:

The American Journal of Human Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2005

13

Ponatinib is a potent inhibitor of wild-type and drug-resistant gatekeeper mutant RET kinase

Mologni, Luca, Redaelli, Sara, Morandi, Andrea, Plaza-Menacho, Ivan, Gambacorti-Passerini, Carlo

Journal:

Molecular and Cellular Endocrinology

Année:

2013

Langue:

english

Fichier:

PDF, 811 KB

english, 2013

14

Mechanisms of RET signaling in cancer: Current and future implications for targeted therapy

Plaza-Menacho, I., Mologni, L., McDonald, N.Q.

Journal:

Cellular Signalling

Année:

2014

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2014

15

Oncogenic RET Kinase Domain Mutations Perturb the Autophosphorylation Trajectory by Enhancing Substrate Presentation In trans

Plaza-Menacho, Iván, Barnouin, Karin, Goodman, Kerry, Martínez-Torres, Rubén J., Borg, Annabel, Murray-Rust, Judith, Mouilleron, Stephane, Knowles, Phillip, McDonald, Neil Q.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 4.38 MB

english, 2014

16

Ras/ERK1/2-mediated STAT3 Ser727 Phosphorylation by Familial Medullary Thyroid Carcinoma-associated RET Mutants Induces Full Activation of STAT3 and Is Required for c-fos Promoter Activation, Cell Mitogenicity, and Transformation

Plaza-Menacho, I., van der Sluis, T., Hollema, H., Gimm, O., Buys, C. H. C. M., Magee, A. I., Isacke, C. M., Hofstra, R. M. W., Eggen, B. J. L.

Journal:

Journal of Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2006

17

Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting.

Plaza-Menacho, I., Mologni, L., Sala, E., Gambacorti-Passerini, C., Magee, A. I., Links, T. P., Hofstra, R. M. W., Barford, D., Isacke, C. M.

Journal:

Journal of Biological Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 519 KB

english, 2009

18

Sorafenib Functions to Potently Suppress RET Tyrosine Kinase Activity by Direct Enzymatic Inhibition and Promoting RET Lysosomal Degradation Independent of Proteasomal Targeting

Plaza-Menacho, I., Mologni, L., Sala, E., Gambacorti-Passerini, C., Magee, A. I., Links, T. P., Hofstra, R. M. W., Barford, D., Isacke, C. M.

Journal:

Journal of Biological Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2007

19

RET-Familial Medullary Thyroid Carcinoma Mutants Y791F and S891A Activate a Src/JAK/STAT3 Pathway, Independent of Glial Cell Line-Derived Neurotrophic Factor

Plaza Menacho, I.

Journal:

Cancer Research

Année:

2005

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2005

20

Focal Adhesion Kinase (FAK) Binds RET Kinase via Its FERM Domain, Priming a Direct and Reciprocal RET-FAK Transactivation Mechanism

Plaza-Menacho, I., Morandi, A., Mologni, L., Boender, P., Gambacorti-Passerini, C., Magee, A. I., Hofstra, R. M. W., Knowles, P., McDonald, N. Q., Isacke, C. M.

Journal:

Journal of Biological Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2011

21

A Role for Glial Cell Derived Neurotrophic Factor Induced Expression by Inflammatory Cytokines and RET/GFR 1 Receptor Up-regulation in Breast Cancer

Esseghir, S., Todd, S. K., Hunt, T., Poulsom, R., Plaza-Menacho, I., Reis-Filho, J. S., Isacke, C. M.

Journal:

Cancer Research

Année:

2007

Langue:

english

Fichier:

PDF, 898 KB

english, 2007

22

GDNF-RET Signaling in ER-Positive Breast Cancers Is a Key Determinant of Response and Resistance to Aromatase Inhibitors

Morandi, A., Martin, L.-A., Gao, Q., Pancholi, S., Mackay, A., Robertson, D., Zvelebil, M., Dowsett, M., Plaza-Menacho, I., Isacke, C. M.

Journal:

Cancer Research

Année:

2013

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2013

23

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking

Dubey, B. N., Lori, C., Ozaki, S., Fucile, G., Plaza-Menacho, I., Jenal, U., Schirmer, T.

Journal:

Science Advances

Année:

2016

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2016

24

RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements

Plaza-Menacho, Iván, Barnouin, Karin, Barry, Rachael, Borg, Annabel, Orme, Mariam, Chauhan, Rakhee, Mouilleron, Stephane, Martínez-Torres, Rubén J., Meier, Pascal, McDonald, Neil Q.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.74 MB

english, 2016

25

RET receptor structure and function in MEN2

Plaza-Menacho, Ivan

Journal:

Endocrine Related Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 711 KB

english, 2017

26

Novel targeted therapeutics for MEN2

Redaelli, Sara, Plaza-Menacho, Ivan, Mologni, Luca

Journal:

Endocrine Related Cancer

Année:

2018

Langue:

english

Fichier:

PDF, 670 KB

english, 2018

27

Hybrid histidine kinase activation by cyclic di-GMPâmediated domain liberation

Dubey, Badri N., Agustoni, Elia, BÃ¶hm, Raphael, Kaczmarczyk, Andreas, Mangia, Francesca, von Arx, Christoph, Jenal, Urs, Hiller, Sebastian, Plaza-Menacho, IvÃ¡n, Schirmer, Tilman

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Fichier:

PDF, 2.96 MB

2020